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Taurine and blood triglycerides: grade C

Limited evidence. Direction: Benefit.

C Limited

Educational guidance, not medical advice

Why this grade

Rubric condition met: Pooled estimates from clinical or undescribed populations with no healthy-only estimate

Three meta-analyses of 12 to 34 randomized trials found lower triglycerides with taurine than with control (mean differences of -13.05 to -18.315 mg/dL). The 2020 meta-analysis reports that most of its trials enrolled patients with liver or metabolic dysregulation, the 2024 meta-analysis was built around metabolic syndrome measures, and none of the abstracts reports an estimate restricted to healthy adults. Under G4 the grade is capped at C.

How we grade evidence

Studies this grade rests on

EffectMixedNo effectSize shows participants (n)202020252030Meta-analysisTzang 2024, 2024: meta-analysis, n = 1,024, result not recordedGuan 2020, 2020: meta-analysis, n not recorded, result not recordedNie 2026, 2026: meta-analysis, n not recorded, result not recorded
each study this grade rests on, by publication year and design. Solid: effect versus the comparator; half-filled: mixed; hollow: no effect; dashed: result not recorded yet. Larger marks had more participants.
Show the numbers
StudyYearDesignParticipantsResult
Guan 20202020meta-analysisnot recordedresult not recorded
Tzang 20242024meta-analysis1024result not recorded
Nie 20262026meta-analysisnot recordedresult not recorded

The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials.

Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials Eur J Pharmacol, 2020. PMID 32871172

Result not recorded
Design
Meta-analysis of 12 RCTs
Population
Mostly patients with liver or metabolic dysregulation (clinical populations)
Funding
not stated

Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.

Tzang CC, Chi LY, Lin LH. Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials Nutr Diabetes, 2024. PMID 38755142

Result not recorded
Design
Systematic review and meta-analysis of 25 RCTs
Sample
n = 1,024
Population
Adults in trials of metabolic syndrome-related measures
Funding
Ministry of Science and Technology, Taiwan, Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) MOST 106-2314-B-002-180-MY3 and MOST 109-2314-B-002-114-MY3, National Taiwan University Hospital, Bei-Hu Branch National Science and Technology, Taiwan

Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials.

Nie Z, Liu Y, Zhang M. Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials Nutr Rev, 2026. PMID 41275513

Result not recorded
Design
Systematic review and meta-analysis of 34 RCTs
Population
Adults in cardiometabolic risk factor trials
Funding
Scientific Research Foundation for Scholars 2022QDL004, Scientific Research Foundation for Scholars of HZNU, Scientific Research Foundation for Scholars of HZNU 2022QDL004

Search and history

Search (): taurine[ti] AND (triglyceride*[tiab] OR lipid*[tiab] OR metabolic syndrome[tiab]) AND (meta-analysis[pt] OR systematic review[pt])

  • Graded C (proposed): Proposed in the monograph draft
  • C to C (approved): Editor sign-off November 13, 2026: grade matches the editor-approved final page